According to the Spanish newspaper El Mundo, some 200 migrants from sub-Saharan Africa attempted to scale the six-metre fence which separates Morocco and the autonomous city in northern Africa on Saturday.
At least 50 of the migrants were left stuck at the top of the fence, which is lined with barbed wire, before being helped to the ground by authorities hours later.
Several of the migrants had to be taken to a nearby hospital with minor injuries.
It is believed to have been the first mass attempt to cross the border into Ceuta since June 4, when around 150 migrants tried to break through the northern border in Benzu.
Perimeter fences preventing the movement of migrants across Europe have become a hot topic after it was announced that £2 million of taxpayers’ money would be used to build a kilometre long wall on both sides of the motorway on the approach to the Calais port.
The section, which is near the notorious Jungle camp has been subjected to a series of attacks by thugs throwing items at traffic to slow them down before attempting to climb onto lorries.
The 13ft structure will replace flimsy fencing that migrants have been able to easily break through and target lorries in a bid to stowaway and make it to Britain.
Official figures show every six minutes a migrant is caught trying to sneak into the UK and there was a total of 84,088 detentions at the British border in the last year alone.
The Jungle camp in Calais houses 10,000 migrants and continues to grow in size on a daily basis.
Immigration Minister Robert Goodwill told the Commons home affairs committee that the wall would restrict the movement of migrants and help keep drivers safe.
Rod McKenzie, a director at the Road Haulage Association, has criticised the government’s planned investment, suggesting that the only answer to stopping the increasing violence is to deploy troops in Calais.
Mr McKenzie said: “The problem is when the wall is only a kilometre long and four metres high, it’s only going to keep migrants from getting on board lorries at that particular point.
“The trouble will just move a few miles further back.
“What we’re seeing is these highly organised gangs of migrants causing blockages on roads, in the approach roads to Calais, which causes a traffic jam and then they use the resulting traffic jam to get migrants on trucks.”